https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:6913 Wed 11 Apr 2018 15:38:21 AEST ]]> Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20085 Wed 11 Apr 2018 12:17:41 AEST ]]> A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9730 8 and ≤ 10 g/dL and ≤ 8 g/dL was more common in the bosentan group. Conclusions: In patients receiving dacarbazine as first-line chemotherapy for metastatic melanoma, the addition of high-dose bosentan had no effect on time to tumor progression or other efficacy parameters. There were no unexpected safety findings. Trial registration: This study is registered in ClinicalTrials.gov under the unique identifier NCT01009177.]]> Wed 11 Apr 2018 09:56:16 AEST ]]>